Derek Wakeman

Derek Wakeman, MD

Medical School

Columbia University College of Physicians & Surgeons


Honors and Awards

Walter A. Ballinger Administrative Chief Resident, 2013-2014

Surgical Jeopardy Finalist at 2010 American College of Surgeons Clinical Congress, October 2010.

SSAT Best Basic Science Quick Shot at Residents/Fellow Conference at DDW 2010, May 2010.

Samuel A. Wells, Jr, MD Resident Research Day Winner (Best Resident Abstract/Presentation for Surgical Science at Washington University)May 2010.


Resident Teaching Award June 2009, 2010


Administrative Lab Resident


Selected Publications

Rowland KJ, McMellen ME, Wakeman D, Wandu WS, Erwin CR, Warner BW. Enterocyte expression of epidermal growth factor receptor is not required for intestinal adaptation in response to massive small bowel resection.
J Pediatr Surg. 2012 Sep;47(9):1748-53.

Wakeman D, Schneider JE, Liu J, Wandu WS, Erwin CR, Guo J, Stappenbeck TS, Warner BW. Deletion of p38-alpha mitogen- activated protein kinase within the intestinal epithelium promotes colon tumorigenesis.Surgery. 2012 Aug;152(2):286-93.

Hitch MC, Leinicke JA, Wakeman D, Guo J, Erwin CR, Rowland KJ, Merrick EC, Heuckeroth RO, Warner BW. Ret
heterozygous mice have enhanced intestinal adaptation after massive small bowel resection. Am J Physiol Gastrointest Liver Physiol. 2012 May 15;302(10):G1143-50.

Wakeman D, Guo J, Santos JA, Wandu WS, Schneider JE, McMellen ME, Leinicke JA, Erwin CR, Warner BW. p38 MAPK regulates Bax activity and apoptosis in enterocytes at baseline and after intestinal resection. Am J Physiol Gastrointest Liver Physiol. 2012 May 1;302(9):G997-1005.

Leinicke JA, Longshore SW, Wakeman D, Guo J, Warner, BW. Regulation of Retinoblastoma Protein (Rb) by p21 Is Critical for Adaptation to Massive Small Bowel Resection. J Gastrointest Surg. 2012 Jan;16(1):148-55; discussion 155.

McDuffie LA, Bucher BT, Erwin CR, Wakeman D, White FV, Warner BW. Intestinal Adaptation after Small Bowel Resection in Human Infants. J Pediatr Surg. 2011 Jun;4 (6):1045-51.

Wakeman D, Longshore SL, McMellen ME, Santos JA, Guo J, Erwin CR, and Warner BW. Extent of Small Bowel Resection Does Not Influence the Magnitude of Intestinal Adaptation in the Mouse. J Pediatr Surg. 2010 Jun;45(6):1274-9.

McMellen ME, Wakeman D, Erwin CR, Guo J, Warner BW. Epidermal growth factor receptor signaling modulates chemokine (CXC) ligand 5 expression and is associated with villus angiogenesis after small bowel resection. Surgery. 2010 Aug;148(2):364-70.

Wakeman D and Warner BW. Urogenital Nonunion – a Rare Anomaly Associated with the Undescended Testis. Am J Surg. 2010 May;199(5):e59-60.

McMellen ME, Wakeman D, Longshore SL, McDuffie LA, Warner BW. Growth Factors: Possible Roles for Clinical
Management of the Short Bowel Syndrome. Semin Pediatr Surg. 2010 Feb;19(1):35-43. Review.

McDuffie LA, Wakeman D, Warner BW. Diagnosis of Esophageal Atresia with Tracheoesophageal Fistula: Need for
Gastrointestinal Contrast? J Pediatr. 2010 May;156(5):852.

Wakeman D, McDuffie LA, Warner BW. Rectal Duplication in an Infant. Surgery. 2009 Dec 2.

Longshore SW, Wakeman D, McMellen M, Warner BW. Bowel Resection Induced Intestinal Adaptation: Progress from Bench to Bedside. Minerva Pediatr. 2009 Jun;61(3):239-51.

Smith DM, Wakeman D, Patel J, Gabriel M. Fornix Lesions Impair Context-Related Cingulothalamic Neuronal Patterns and Concurrent Discrimination Learning in Rabbits. Behavioral Neuroscience. 2004 Dec;118(6):1225-39.

Abstracts/Presentations

Wakeman D, Schneider JE, Liu E, Wandu S, Guo J, Erwin CR, Stappenbeck TS, Warner BW. Deletion of p38-alpha within Enterocytes Promotes Colon Tumorigenesis. Academic Surgical Congress 2012, oral presenation.

Choi PM, Wakeman D, Leinicke J, Guo J, Warner BW. Inducible Deletion of Rb in Intestinal Epithelium Enhances Adaptation after Small Bowel Resection. Academic Surgical Congress 2012, abstract.

Rowland KJ, McMellen ME, Wakeman D, Wandu WS, Erwin CR, Warner BW. Epidermal Growth Factor Expression in Enterocytes is Not Required for Intestinal Adaptation Following Small Bowel Resection. American Academy of Pediatrics 2011, abstract.

Wakeman D, Schneider JE, Liu E, Wandu S, Erwin CR, Guo J, Stappenbeck TS, Warner BW. Deletion of p38-alpha within Enterocytes Promotes Tumorigenesis. Missouri chapter of American College of Surgeons meeting 2011, oral presenation.

Wakeman D, Guo J, Santos JA, Schneider JE, Leinicke JA, Rowland KD, Erwin CR, Warner BW. Intestinal Resection-Induced Enterocyte Apoptosis is Mediated by p38á MAPK-directed Activation of Bax. Digestive Disease Week 2011, Oral Presentation.

Leinicke JA, Longshore SW, Wakeman D, Guo J, Warner, BW. Regulation of Retinoblastoma Protein (Rb) by p21 Is Critical for Adaptation to Massive Small Bowel Resection. Digestive Disease Week 2011, abstract.

Lu J, Garcia AM, Wakeman D, Rowley C, Warner BW, Levin MS, Rubin DC. Tis7 Deletion Reduces Survival and Body Weight Recovery in Mice Following 50% Small Bowel Resection.  Digestive Disease Week 2011, abstract.

Leinicke JA, Longshore SW, Wakeman D, Guo J, Warner, BW. Retinoblastoma Protein (pRb) Is Indispensible for Adaptation to Massive Small Bowel Resection. Academic Surgical Congress 2011, Abstract. 

Wakeman D and Bucher B. Invited discussant at 2010 American College of Surgeons Clinical Congress Surgical Jeoprady Competition.

McDuffie LA, Bucher BT, Erwin CR, Wakeman D, White FV, Warner BW. Intestinal Adaptation Following Small Bowel Resection in Human Infants. American Academy of Pediatrics 2010, abstract.

Wakeman D, Leinicke LA, McMellen ME, Guo J, Erwin CR, Warner BW. Intestine-Specific Deletion of p38á MAPK Perturbs Enterocyte Kinetics Following Massive Small Bowel Resection. Digestive Disease Week 2010, Oral Presentation.

Chapters

Wakeman DS, Leinicke JA, Warner BW: Short bowel syndrome. In: Succeeding in Paediatric Surgery Examinations: Volume 1 (Antao BA, Irish MS, eds.). Radcliffe Medical Press Ltd, London UK, 2012.

Leinicke JA, Wakeman DS, Warner BW: Short bowel syndrome. In: Succeeding in Paediatric Surgery Examinations: Volume 2 (Antao BA, Irish MS, eds.). Radcliffe Medical Press Ltd, London UK, 2012.

Wakeman D and Southard RE. Burns. In: The Washington Manual of Surgery, 6th ed (Klingensmith et al, eds.). Lippincott Williams & Wilkins, Philadelphia, PA, 2011.